Pyrrolo[2,3-c]pyridine-2-carboxylic acid
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid
CAS: 67058-74-6
Molecular Formula: C8H6N2O2
Pyrrolo[2,3-c]pyridine-2-carboxylic acid - Names and Identifiers
Pyrrolo[2,3-c]pyridine-2-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C8H6N2O2 |
| Molar Mass | 162.15 |
| Density | 1.506 |
| Melting Point | 194-195℃ |
| Boling Point | 471.131 °C at 760 mmHg |
| Flash Point | 238.731 °C |
| Storage Condition | 2-8°C |
Pyrrolo[2,3-c]pyridine-2-carboxylic acid - Introduction
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is an organic compound with the chemical formula C8H5NO2. The following is a description of its nature, use, preparation and safety information:
Nature:
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is a solid powder with a white to light yellow appearance. Its melting point is about 170-173°C. It is less soluble in water, but soluble in common organic solvents such as ether and methanol. It is a compound with a carboxyl group and has a certain acidity.
Use:
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is an important organic synthesis intermediate, widely used in the pharmaceutical and pesticide fields. Its derivatives can be used in the research and development of kinase inhibitors, antitumor drugs and antiviral drugs.
Preparation Method:
A method for synthesizing 1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is obtained by reacting 2,3-dichloropyridine with pyrrolidinol under the catalysis of a base. The specific synthetic route and conditions can be adjusted as needed.
Safety Information:
1H-Pyrrolo[2,3-c] The specific safety information for pyridine-3-carboxylic acid may depend on its specific physical and chemical properties. Because it is a compound with a carboxyl group, it may be irritating to the eyes, skin and respiratory tract. Appropriate protective measures should be taken during operation, such as wearing chemical gloves and protective glasses, and ensuring a well-ventilated laboratory environment. Please read the relevant safety data sheets before use and follow the safety procedures.
Nature:
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is a solid powder with a white to light yellow appearance. Its melting point is about 170-173°C. It is less soluble in water, but soluble in common organic solvents such as ether and methanol. It is a compound with a carboxyl group and has a certain acidity.
Use:
1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is an important organic synthesis intermediate, widely used in the pharmaceutical and pesticide fields. Its derivatives can be used in the research and development of kinase inhibitors, antitumor drugs and antiviral drugs.
Preparation Method:
A method for synthesizing 1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid is obtained by reacting 2,3-dichloropyridine with pyrrolidinol under the catalysis of a base. The specific synthetic route and conditions can be adjusted as needed.
Safety Information:
1H-Pyrrolo[2,3-c] The specific safety information for pyridine-3-carboxylic acid may depend on its specific physical and chemical properties. Because it is a compound with a carboxyl group, it may be irritating to the eyes, skin and respiratory tract. Appropriate protective measures should be taken during operation, such as wearing chemical gloves and protective glasses, and ensuring a well-ventilated laboratory environment. Please read the relevant safety data sheets before use and follow the safety procedures.
Last Update：2024-04-09 21:04:16
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